Are you getting antioxidant skin protection to counter the effects of sun radiation with your current skin care regimen?

You know that free radicals or Reactive Oxygen Species (ROS) and UVA damage disrupt the cell communication system and the balance of growth factors and proteins released by cells of the immune system, which act through specific cell receptors to regulate immune responses, resulting in abnormal cell function, including the breakdown of collagen, and the aged appearance of skin and loss of skin elasticity.

While UV radiation is the most commonly cited type of environmental stress, other factors, such as cigarette smoke and air pollution, can cause oxidant formation on the skin surface and accelerate skin aging.

When considering skin care, remember this: With a more rapidly depleting ozone layer, the need for sun protection is greater than ever before. Sunscreens, while effective barriers, only physically hinder UV damage. A second line of defense is imperative…. That second line of defense is BIOBALM.

Featured Skin Antioxidant Cream

BIOBALM contains the most complete and balanced natural antioxidants, enhancers of cell communication and cellular detoxifiers for routine application on the skin surface. It halts the chain reaction of free radicals that are missing electrons and calms them before they tear into your cells.

BIOBALM skin treatment brings your tissues back into balance, e.g. restores integrity to your cell membranes.

• Enhances cellular detoxification
• Inhibits free radical production caused by UV and H2O2
• Provides cellular and DNA protection from UV damage

Potent Antioxidant Cream
The skin treatment balm contains hyaluronic acid and a biological ingredient with other glycosaminolycans and enzyme-proteins tightly bound to oligoelements (Copper and Zinc) that act as co-enzymes and have antioxidant activity. They are your immune system workers that quench free radicals and protect your skin from the effects of UVA radiation.

The biological ingredient in the balm also contains and induces the proliferation of antimicrobial peptides that stop microbes from invading your tissue-proteins.

Also present are glycoconjugates that have the ability to tell a skin cell to act and behave better, more like a normal healthy skin cell would, or to stop other substances from telling the cell to behave abnormally.

This is exciting news because antioxidants lack the ability to "tell" a damaged skin cell to behave more normally. Years of unprotected or poorly protected sun exposure causes abnormal skin cells to be produced. Instead of normal, even, and completely intact skin cells being regenerated, when damaged cells form and reproduce they are uneven, flat, and lack structural integrity. As a result of these deformities, they behave poorly. This is where cell-communicating ingredients (examples are glycosaminoglycans, glycoproteins, niacinamide and adenosine triphosphate) have the potential to help.

Every cell has a vast series of receptor sites for different substances. These receptor sites are the cell’s communication hookup. When the right ingredient for a specific site shows up, it has the ability to attach itself to the cell and transmit information. In the case of skin, this means telling the cell to start doing the things a healthy skin cell should be doing. If the cell accepts the message, it then shares the same healthy message with other nearby cells and so on and so on.

As long as there is a receptor site and the appropriate, healthy signaling substance, a lot of good, healthy communication takes place. But a cell's communication network is more complex than any worldwide telephone system ever made. The array of receptor sites and the substances that can make connections to them make up a huge, complex, and varied group with incredible limitations and convoluted pathways that is the field of study of glycobiology a the new "sweet science" of polysaccharides. Communication between cells affects many of the cell's behaviors, e.g. motility, cell division, differentiation, programmed cell death, and cellulat detoxification.

Cellular detoxification is the process by which the body removes cellular and DNA damaging materials that are responsible for adverse effects on the skin. In the presence of oxidizers such as UV and H2O2, ROS are formed on the skin surface, which can modify cellular function.

Antioxidant skin care, antioxidants skin, anti aging antioxidant skin care product
There are natural antioxidants, such as catalase and glutathione that exist within cells. They assist in limiting ROS levels since an overabundance will negatively impact the integrity of the cells. Specifically, catalase inhibits the production of ROS following UV exposure, while glutathione’s primary function is to remove damaged proteins from the cells. Glutathione (GSH), often called the “master anti oxidant”, binds itself to proteins damaged by oxidation, allowing these toxins to be excreted from the body. This process is known as glutathionylation. Unfortunately, as the body ages, glutathione production decreases resulting in a decrease in detoxification.

Skin antioxidants and their role against free radical photodamage and photo-aging
Say you expose yourself to the sun for a while; some of the molecules in your skin may become short of one electron so they grab an electron from a lipid in the skin membrane. The "oxidized" lipid then steals an electron from the next lipid in the skin membrane, leaving it unpaired and desperate. And so the stealing is repeated down the line, in a chain reaction.

When free radicals do this – grab electrons from your body molecules – the molecules are oxidized and left with an "electron hole."

Holes in our cell membranes allow unwanted elements in, like leaving your car door unlocked in a high-crime area. Extra anti-oxidants are essential to staying healthy.

You've heard that free radicals damage cell structures and cell processes. They are the first cause of all disease and early aging because we are the totality of our cells.

You know that free radicals are out to grab electrons, they're electrophilic (electron-lovers). And the phospholipids in our cell membranes are the easy prey of free radicals. These lipids are unsaturated fats who beg to give their electrons away. In fact, they're so attractive to oxygen, that it's the cell's main way of keeping infectious organisms out, like bacteria, fungi, viruses.

What quenches a free radical? What stops it in its tracks? An atom that has electrons to give, that will satisfy the radical's electrophilia.

Who decides whether an atom will steal electrons from other atoms, OR give its electrons away, OR like a good child will share its electrons?

It's in the chemistry of the atom. Picture an atom with its electrons orbiting round the nucleus, each in their own orbit, like planets orbiting the sun. Now it's the electrons in the outer orbit, the shell furthest away from the sun, that count in chemical reactions. 

If an atom's outer shell has more than half – but not all – the electrons it needs, then it's a free radical. It will steal electrons from other atoms. Also called an oxidizer, oxidizing agent, electron acceptor, or Lewis acid.

Oxygen has 6 electrons in its outer shell, it needs 8, therefore it has more than half, and it's out on the prowl, looking for 2 electrons to bring its outer fill to 8. It's a virulent oxidizer!

If an atom's outer shell has less than half the electrons it needs, then it's a free radical quencher or scavenger. It will give electrons to other atoms. Also called a reductant, reducing agent, electron donor, or Lewis base. All alkaline minerals are reductants. They walk around freely handing out their outermost electrons. So they can enter into the chemistry of life.

For instance, calcium and magnesium have only 2 electrons in their outer shell, while sodium and potassium have one each. It's far easier to give up their one or two electrons than prowl around for a whole bunch.

All free radicals, all acids, all carcinogens, are electron-loving, eager to gain electrons. Once in our blood, they strongly react with electron donors such as our cell membranes.

These villains stick to our cell membranes and smother the poor cell. They barricade the city-cell – no food can come in, no waste can go out. They also burn holes in cell and nuclear membranes and attack your DNA, causing mutations there.

Plus they neatly fit into protein receptors in your cell membranes, receptors that need to receive signals from your brain and endocrine glands (hormones) to tell your cell what to do. We all know pesticides are estrogen-mimickers.

With no signals, an isolated cell doesn't know what to do, and begins to multiply itself out of control. What is this? Cells dividing over and over into a big lump? It's a tumor, benign or malignant.

Key Points about UV Damage:
• American Academy of Dermatology estimates that 80% of a person’s lifetime sun damage occurs before the age of 18.
• More melanin does not equate to less risk. Even skin with higher melanin content can incur significant DNA damage at very low UV exposures.
• UVA, the longer wavelength, is believed to contribute to wrinkle formation.
• UVB attacks the skin surface and has been shown to be a major contributor to skin cancer formation.

Topically-applied antioxidants help to keep skin healthy and help prevent sun damage and improve cell function. Further, skin antioxidants have been conclusively shown to exert a positive effect on reducing skin irritation and inflammation, and that is a crucial step in creating or maintaining healthy, vibrant skin and, therefore potentially reducing accelerated skin aging and wrinkles.

In and around cells, the skincare ingredient that is embodied in our products, as we will review further below, quenches free radicals before they can damage the molecules of healthy skin cells. Your cells are protected and allowed to grow, function, and regenerate without interference from rogue, oddball radicals that steal their electrons.

BIOBALM brings your tissues back into balance, e.g. restores integrity to your cell membranes. The product contains natural enzyme-proteins and glycoproteins, your immune system workers, that quench free radicals and protect your skin from the effects of UVA radiation, while at the same time it stops microbes from invading your tissue-proteins. It also moisturizes the skin deep within where it matters. And it helps to quickly repair damaged skin tissues by dissolving them, through the action of those enzymes, into their amino-acid components; which are then used to rebuild strong membrane proteins to strengthen the cell's defences.

BIOBALM allows the skin to respond better to sun damage and aging and may also improve the production of key components of the skin affected by photodamage and photoaging.

The biological ingredient in BIOBALM also moisturizes the skin deep within where it matters. And it helps to quickly repair damaged skin tissues by dissolving them, through the action of enzymes, into their amino-acid components; which are then used to rebuild strong membrane proteins to strengthen the cell's defences.

Stop procastinating about your deteriorating looks. Now you can start taking heed of what your skin is telling you.

What if we convince you that it is in your best interest to follow a routine daily regimen that uses just ONE product packed with anti aging antioxidant enzymes and activators of skin regeneration, for a lifetime of healthier skin?

Are you willing to be generous with yourself and invest a few cents and minutes a day to maintain and protect that cherished face and most visible asset of yours, for years to come, in good shape and looks?

BIOBALM contains, instead of botanical "actives" or "cosmeceuticals", discovered or designed by some clever pharmacist, a natural ingredient that will lead you to a lifetime of healthy skin. We guarantee you’ve never heard anything like it!

The most common anti oxidants currently used in skin care products include alpha lipoic acid, beta-glucan, coenzyme Q10, curcumin, grape seed extract, antioxidant green tea , soybean sterols, superoxide dismutase, vitamin A (retinyl palmitate and retinol), vitamin C (ascorbyl palmitate and magnesium ascorbyl palmitate), vitamin E (alpha tocopherol, tocotrienol), and extracts from lemon and rosemary.

A problem with many of those commercial antioxidants included in skin care products that are said to prevent premature aging or retard the aging process is that they oxidize quickly and therefore their efficiency declines with time. Vitamin C, for example, oxidizes rapidly and is sensitive to high temperatures. This is also true of the anti oxidant EGCG which is found in green tea, and vitamin E. As opposed to these, the antioxidant in the serum solution that we describe fully in this website is already a solution in water, does not need to be heated to incorporate it into cosmetic formulations and does not oxidize easily, and thus remains effective over time.

In fact our "solution" is the ONLY all-natural ingredient found in NATURE created by a little animal, a land snail that is abundant in most vineyards, to protect its own cells, skin proteins and intercellular matrix from free radicals, UVA radiation, and much more.

This little creature uses a complex antioxidant serum (a soluble or fluid substance made up of many complex molecular chains that comprise glycans, peptides and proteins, enzymes and co-enzymes and oligoelements) to protect its skin from oxygen radicals when it comes out of its shell after resting or hybernating and to repair its skin whenever damaged. It also uses this substance to trigger the proliferation of antimicrobail peptides and avoid beeing affected by attacks from opportunistic micro-organisms always ready to intrude when skin is injured. Now, isn't that truly amazing! As a result, snails never suffer from skin infections – can you imagine?

But what does this serum antioxidant have to do with human skin? -you may thoughtfully be asking!

Well, it happens that the creature's skin is made of very much the same molecules and structures that human skin is made of: collagen, elastin and fibrin protein fibers and water holding sugars: glycosaminoglycans and glycoproteins (sugars bound to proteins) and the same types of cells.

Snails use their solution to moisturize, repair, renew and protect their skin while they thrive exposed nude to the sun rays and the hazards of the environment, pretty much like we merry around exposing our nude face. It is also the mechanism they use to protect their body from both oxygen radicals when they go out of their shell after hibernating and from the damaging effects of solar radiation.

Land snails crawl over a variety of potentially contaminated surfaces and the snail foot could be the primary site of entry for pathogens, parasites and a range of opportunistic organisms, so it is not much wonder they must have a defensive system to protect them. Such mechanism is a silvery secretion they produce whenever they are under stress and different than the one they leave behind while crawling.

Since the 19th century there has been a renewed interest in the pharmaceutical and medical use of snails, particularly for dermatological applications.

But the most common purpose for raising snails in modern times has been for food. That is, until a snail farm in Chile noticed that their snail handlers had exceptionally smooth hands, and any cuts or abrasions to their hands healed unusually quickly and without scars.

Scientific screening of the components of the snail's threapeutic fluid has shown it contains peptides that form pores in microbial membranes and disrupt their integrity while at the same time they trigger skin regeneration. The fluid is a biological complex compound of glyco or sugar chain molecules bound to proteins, peptides, enzymes, coenzymes and Copper, Calcium, Zinc and Iron present in nanomolecular amounts as trace oligoelements. Using proprietary technology, no harm is inflicted upon the snails during the collection process.

As we mentioned before, screening also shows that the skin of these little creatures is made of the same structures present in human skin: — the same collagen and elastin connective tissues, and the same water holding glycosaminoglycan and proteoglycan molecules, etc.—. No wonder it works so well for a large array of those bothersome skin afflictions we humans suffer from.

Scientific Validation

Link: Skin Regeneration Properties of Mollusk Secretion Copyright © 2007 S. Karger AG, Basel

This scientific report confirms previous studies done in Spain (1998-2001) on some of the cellular and molecular effects underlying the observation that the snail secretions have regenerative effects on human skin.

• Has powerful enzyme antioxidant SOD (Superoxide Dismutase) and GST (Glutathione - often called the “master anti oxidant") activities as well as other multiple low molecular antioxidants that act at the level of free radical production and also sequestrate free radicals.
• Stimulates fibroblast proliferation and reorganization of the actin cytoskeleton of cells.
• Stimulates extracellular matrix assembly and the action of regulatory proteins known as Tissue Inhibitors of Metalloproteinases (TIMPs) responsible for the reversible inhibition of metalloproteinase (MMP) enzymatic activities, which limits the extent of the damage during wounding and scar formation and attenuates the signs of aging by reducing the degenerative effects of excessive MMP activity.

Together, these effects provide a broad array of molecular mechanisms that explain the cellular regeneration induced by the secretion and supports its use in regenerative therapy at the molecular level.

Clinical Trials

Two studies providing clinical evidence of the beneficial effects of the snail serum on human skin are summarized here: one is on the effects of the snail serum on people affected by photo-aging and another is about the effect of the ingredient on patients diagnosed with breast carcinoma, about to initiate or undergoing radiotherapy treatment.

Evaluation of the Anti-Wrinkle and Reaffirming Efficacy of a Cryptomphalus Aspersa-based Product (CAS) in the Treatment of Skin Photoaging M.J. Tribó, E. Serra-Baldrich, M. Asin, J.A. Camarasa. Dermatología & Cosmética, March (vol IX), 1999.

Ultraviolet light as well as frequent contact with harmful environmental chemicals such as ozone leads to the formation of excessive quantities of reactive oxygen species on the skin. Free reactive oxygen radicals cause destruction of biomembranes by oxidizing unsaturated fatty acids and protein oxidation in human as well as depolarization and crosslinking of biopolymers. This induces a spectrum of well documented acute responses such as erythema, hyperproliferation, desquamation and with chronic irritation a general degradation of collagen together with an accumulation of abnormal elastin deposits in the dermis resulting in premature skin aging.

The skin’s own defense system is mainly based on an entire functionality of superoxide dismutase (SOD). Endogenic SOD is found at high levels in the stratum corneum but only low baseline levels were found in the dermis. In photoaged skin, a significant depletion of antioxidants enzyme expression was observed within the strateum corneum and in the epidermis. The endogenous level of SOD decreases significantly. A replacement by using cosmetic formulations is therefore a must. Externally applied SOD is able to penetrate into the intact stratum corneum and reach the upper layers of the epidermis, as has been shown using the fluorescent dye (FITC) labeled enzyme.

This report confirms a protective effect of the snail secretions in topical application against UV induced cutaneous damage and to overcome a lack of endogenic SOD to restore the antioxidative homeostasis of the skin.

The study focused on five aspects of skin aging due to excessive sun exposure.

A cream formulated with the snail serum was applied to the face of 32 individuals who showed signs of facial photoaging for an eight-week period on a continuous basis. The subjects were evaluated at 2, 4 and 8 weeks of treatment using a clinical evaluation method and the results were correlated with those seen with the use of instrumental techniques. Subjects also kept a subjective journal of their own observations and feelings towards the product which were evaluated at the end of the study.

The results of the study were very positive, affirming the snail serum as a true treatment in the fight against photoaging. Both according to the measurements taken by the instruments and image analysis programs, wrinkle depth is substantially aided by the product. Hydration is significantly improved due to the moisture retaining ability the serum imparts to skin.

Not only were the results processed by the instruments used to measure them positive, the subjects all had positive visual results, according to their journal entries. All study participants were happy with the topical treatment of photoaging in the study. Firmness, elasticity, and all the other side effects of excessive sun exposure were improved using the product with snail serum as a topical agent. Users' subjective comments indicate considerable comfort and satisfaction with the results of the experience.

Comments: the study was done in 1999 with the snail serum as part of a base cream that is different than the ingredients and technology we use in BIOCUTIS products which allows for a more deeper penetration of the serum into the skin and its proper release within the target cells.

The clinical efficacy of a cosmetic product is rarely confirmed by histological and immunohistochemical analyses. Our in-vivo studies with 15 women aged 35-65 of Fitzpatrick skin types II and III confirm that treatment with the snail serum leads to significant subjective (clinical signs and satisfaction) and objective (profilometry) improvements in cutaneous photoaging, confirmed by the improvement of subjects histopathological condition.

Clinical Efficacy of Radiocare® (based on cryptomphalus aspersa secretions) in the Prevention & Treatment of Acute Radiodermatitis. Santos M, Delgado JM, Rodríguez S, Saez J, Errazquin L, Palacios A, Bouché A, Andreu FJ, Sancho S, de las Heras MH, Alonso A, Escó R, Velasco J, Maciá M, Calvo F, Meirió F. Gicor. Grupo Español de Investigación en Oncología Radioterápica.(2007).

This recent study conducted at a Hospital in Madrid, Spain has evaluated the efficiency and tolerance of a product which includes snail secretion and is made by a Spanish pharmaceutical company, in the prevention and treatment of acute radiodermatitis (Grade: I-II) in patients diagnosed with breast carcinoma, about to initiate or undergoing radiotherapy treatment.

Type of study: Open, controlled, multicentric study.
Population: 96 women, diagnosed with breast carcinoma, mean age of 55 years. Irradiation model: Early breast cancer: (50Gy / 25 fractions of 200cGy / 5wks + 10-16 Gy to the tumor area).
Design: Patients were divided into three groups:

1. Control  (Standard treatment): 22 patients, who received normal treatment, according to the degree of skin toxicity.
• No toxicity: No treatment.
• Grade I toxicity: Camomile water
• Grade II toxicity: Topic corticosteroids (Fluocinolone acetonide) 1/d

2. Preventive snail serum: 33 patients, who used snail serum preventively, once a day, from the beginning of radiotherapy to its end.

3. Curative snail serum: 41 patients undergoing radiotherapy, who used snail serum if they presented acute radiodermatitis lesions, grades I and II. Every patient within this group received daily treatment with snail serum  from the moment of detection of the wounds until their remission.
Clinical and photographic evaluation: Initial evaluation, followed by weekly revision during radiotherapy treatment. After completion of the radiotherapy, repeated evaluations were conducted after 1, 2 and 4 weeks. Toxicity was scored according to benchmark objective criteria and to patients symptoms: itching, pain, erythema, desquamation.

Evaluation of the level of satisfaction of both the patient and the investigator was done for different aspects such as product presentation, handling, tolerance and therapeutic efficiency.

Conclusion: Results have demonstrated the efficiency of treatment with snail secretions in the resolution of Acute Radiodermatitis, in a statistically similar fashion or even better compared to standard treatment.

According to these results, treatment with a product with snail secretions:

• Does not cause adverse effects, not even during prolonged therapy.
• It does not interfere with radiotherapy.
• Employed in a Curative or Preventive way, it is as efficient as Standard treatment (camomile water and corticosteroids) or even better.
• Preventive treatment is significantly more beneficial regarding evolution of radiodermatitis.
• Products with snail serum have been favoured by both Patients and Investigators, being more satisfactory than Standard treatment.

The regenerative mechanism of action of the snail secretion results in clinical amelioration of lesions caused by Acute Radiodermatitis, supporting its predominance over emolients. The lack of local and/or systemic adverse effects in long treatments provide a rationale for its election instead of topic corticosteroids.

POWERFUL ANTIOXIDANT SKIN CARE PRODUCT

Nature's gift for healthy skin™

The fluid is a complex compound of powerful water soluble proteoglycans, glycosaminoglycans, protein enzymes, copper peptides, antimicrobial peptides and Copper, Zinc, Calcium and Iron oligoelements. And although highly valued by medical scientists and the cosmetic industry for their biological activity it has not been possible to synthesize them in even the most sophisticated biotechnological laboratory.

The fluid is the most original, complete and balanced solution for skin care created by a living creature to protect, restore integrity without leaving scars behind, renew and moisturize its own skin (its own collagen, elasting, water holding molecules and other skin structures which are very much the same human skin is made of).

It acts on human skin as a biological activator of both the elimination of dead and damaged skin cells and the orchestrated renewal of all the elements of healthy skin. And controls folliculitis of the skin and scalp and facial and body acne.

Natural & Biological Ingredients in BIOBALM

(1) Purified Water;

(2) Snail Serum Glycoconjugates, the richest biological adaptogen for healthy skin yet known, created by a living creature to function as a biological antimicrobial, inflammatory-moderator, antioxidant, skin moisturizer & trigger of scarless healing & skin regeneration;

(3) Rose Hip Seed Oil a rich natural source of trans retinoic acid (a natural precursor of Vitamin A) and polyunsaturated essential fatty acids (EFAs), Linoleic and Linolenic, 77%, which replenish dry and damaged skin and naturally promote elasticity and firmness.

(4) Olive Oil emulsifier, surfactant, and squalene derivatives that replenish the lipid content of the skin blocking the penetration of allergens and toxins and act as antioxidants;

(5) Seaweed Extract a rich source of oligoelements that are necessary for cellular growth,

(6) Hyaluronic Acid moisturizer a naturally occuring skin substance capable of holding more water than any other known hydrator;

(7) Chamomile for inflammatory skin conditions. It is good for sensitive skin, and helpful in dermatitis;

(8) Pentavitin™, Saccharide Isomerate, a carbohydrate complex similar to that found in the stratum corneum of the skin that retains water by tightly binding water to keratin;

(9) A preservative made only with the following botanical extracts in minute quantity: Origanum Vulgare (Oregano) Leaf Extract (and) Thymus Vulgaris (Thyme) Extract (and) Cinnamomum Zeylanicum (Cinnamon) Bark Extract (and) Rosmarinus Officinalis (Rosemary) Leaf Extract (and) Lavandula Augustifolia (Lavender) Flower Extract (and) Citrus Medica Limonum (Lemon) Peel Extract (and) Mentha Piperita (Peppermint) Leaf Extract (and) Hydrastis Canadensis (Golden Seal) Root Extract (and) Olea Europaea (Olive) Leaf Extract; and nothing else.

SKIN CARE FROM DIFFERENT PERSPECTIVES
Dermatologists say BIOBALM performs three coordinated functions: 1) supports your immune system and helps it recognize non functional and damaged tissues 2) degrades the disfunctional, damaged, dying or dead tissues into their basic amino-acid and other components and releases them for regeneration of healthy skin cells and 3) orchestrates the reconstruction of all the components of the skin matrix by triggering the proliferation of all its healthy structures.

A cosmetic formulator would tell you the biological ingredient in BIOBALM ™ is a balanced and complete solution for skincare. Protects, repairs, renews and moisturizes the skin.

Mario Reyes, a scientist engaged in the development of new knowledge in the newest branch of biological sciences, the science of glycobiology, says the fluid secretion is made of complex molecular conjugates: glycoproteins, sulfated acidic glycosaminoglycans, proteoglycans, enzymes and coenzymes. These are molecules of particularl importance for effective communication among cells. They play a crucial role in transmitting important biochemical signals into and among cells. In this way, these carbohydrates (sugars) guide the cellular communication that is essential for normal cell and tissue development and physiological function.

Glycobiology is a relatively new branch is science (1988) that attempts to understand how sugars in the body -called glycans- contribute to human health and contain information as necessary to define the complexity of life as that of DNA and proteins.

From the consumer’s perspective:

BENEFITS OF THE BIOLOGICAL INGREDIENT BASED ON SCIENTIFIC EVIDENCE

1) Removes dead, dying and denatured skin cells. It does so by the action of enzyme digestion (dissolution by hydrolysis) which reduces blemishes, gently dissolves plugs of clogged pores, imperfections, scars, stretch marks, and keratosis on the surface of skin instead of aggresively polishing them out as exfoliation or glycolic acid chemical peels do.

2) Promotes cell proliferation and new synthesis of collagen, elastin, and the water holding molecules within the skin (hyaluronic acid and other glycosaminoglycans).

Collagen provides strength, elastin the elasticity, and glycosaminoglycans and proteoglycans the moisture and plumpness of the skin. With aging, the thickness of the dermal layer is reduced and this is partially responsible for the formation of wrinkles in aging skin.

3) Helps remodel and speed turnover of the basal membrane of the skin

4) Anti oxidant - provides protection from the effects of UV radiation and free radicals: photo-protective action.

Specific studies show the following antioxidant activities in the biological ingredient:
a) enzymatics as superoxide dismutase (SOD proteins cofactored with copper and zinc and iron),
b) conjugation enzymes as glutathione-S-transferase and c) low molecular weight antioxidants.

Zinc protects against UV radiation, enhances wound healing, contributes to immune and neuropsychiatric functions, and decreases the relative risk of cancer and cardiovascular disease. All body tissues contain zinc; in skin, it is five to six times more concentrated in the epidermis than the dermis. Zinc is required for the normal growth, development and function of mammals. It is an essential element of more than 200 metalloenzymes, including the antioxidant enzyme, superoxide dismutase, and affects their conformity, stability, and activity. Zinc also is important for the proper functioning of the immune system, and for glandular, reproductive and cell health. Abundant evidence demonstrates the antioxidant role of zinc. Topical zinc, in the form of divalent zinc ions provides antioxidant photoprotection for skin. Zinc ions may replace redox active molecules, such as iron and copper, at critical sites in cell membranes and proteins; and alternatively, zinc ions may induce the synthesis of metallothionein, sulfhydryl-rich proteins that protect against free radicals. Topical zinc ions provide an important and helpful antioxidant defense for skin.

Antioxidant activities of the snail serum benefit the cells in the skin by:
• Inhibiting Reactive Oxygen Species (ROS) generation and free radical sequestration effects.
• By protecting the cells against UVA radiation, with double the antioxidant activity of Quercetin Flavonoids and Troloc C, a water-soluble vitamin E analog, used as control antioxidants in this type of studies.

5) Breaks down denatured proteins into its amino-acid components, which otherwise cause inflamm-aging, and releases those for rebuilding of the skin structures.

6) Hydrates the skin from within because it promotes the proliferation of glycosaminoglycans, the molecules that hold in water in the skin. This strengthens and firms the skin, thus preventing tearing of skin that may show as stretch marks and avoiding sagging.

The surface structure we see as skin (the intercellular matrix) is made up of many different components, ranging from ceramides to lecithin, glycerin, polysaccharides, hyaluronic acid, sodium hyaluronate, sodium PCA, collagen, elastin, proteins, amino acids, cholesterol, glucose, sucrose, fructose, glycogen, phospholipids, glycosphingolipids, glycosaminoglycans, proteoglycans and many more.

All of these give the skin what it needs to keep its cells intact. Just adding water is meaningless if the intercellular matrix is damaged. When a moisturizer does contain a combination of these natural moisturizing factors (NMFs) and water-binding ingredients, it can help reinforce the skin's natural ability to function normally, improve skin's texture, and with continual use of products containing the ingredients mentioned above, can eliminate dry skin.

BIOBALMCREAM - ORGANIC SKIN CARE CREAM WITH NATURAL INGREDIENTS
BIOBALM ™ products combine nature's wisdom with a biotechnology that stabilizes and protects the glycoconjugates from degrading by placing them in liposomes, which secures their bioavailability and proper release deep within the skin.

BIOBALM ™ is formulated to transform a complex substance that is an antioxidant fluid with cell-communicating ingredients and biological activators of skin renewal into a natural skin moisturizing cream. A treatment cream that also moisturizes, replenishes and stabilizes the lipid content within the intercellular skin matrix.

This is achieved by adding natural emollients, emulsifiers, surfactants and nourishing extracts derived from Olive Oil, hydrating Hyaluronic acid, and humectant Glycerin.

The Olive Oil derivatives in the formulation make the liquid biological ingredient into a cream, especially Squalene -which is also an antioxidant-, and replenish the lipid barrier of the skin.

Moisturizing Cream: Hyaluronic Acid, Glycerin, and Squalene in the cream contribute to your skin’s hydration and have long term effects on the capacity of skin to hold in water.

Preservative: To safely preserve the product from microorganisms, yeasts and moulds, a skin-friendly pH-stable preservative system is incorporated. It combines a widely used, globally-accepted preservative (including Japan ), phenoxyethanol, with a proven preservative-enhancer, ethylhexylglycerin, that have none of the controversial side effects of cheap parabens used in most cosmetic products.

HEALTHIER & BEAUTIFUL ROUTINE
Apply the skin care cream on clean and pat dry skin twice daily. More is not necessarily better, but to ensure optimum results application on older blemishes or more affected areas should be repeated more frequently. Results are cumulative and become permanent.

Use the cream as a belly balm to prevent stretch marks from the third month of pregnancy and continue for three months after child birth. See further below our offer for the BIO STRETCH MARK CREAM, which is the same as BIOBALMin a larger container and with a twist that is better suited for pregnancy and to simultaneously get rid of cellulite.

Use BIOBALM ™ on raised hypertrophic scars or on stretch marks in conjunction with strong massage and exfoliation to eliminate dead skin cells or try our BIOSKINEXFOL cream to break down old and rough stretch marks presented further below.

Apply BIOBALM ™ on keloids after cleansing with a salicylic pad. Use on dry face after washing the face with lukewarm water for the relief of rosacea or skin rashes. Use it after shaving to prevent and heal ingrown hairs and razor bumps.

BIOBALM™ is recommended for use before and after skin resurfacing procedures such as chemical peels, dermabrasion, micro-dermabrasion or laser surgery.

The cream is also a unique nutrient-rich moisturizer for wrinkles on the face, the delicate eye area, neck, and body. It promotes balanced skin renewal. Treatment should be continued until desired results are achieved. Or, try our new BIO SKIN REJUVENATION cream to even your skin tone and get rid of age spots.

If your skin is too oily and you wish to use an oil free product try our BIOSKINCLEAR oil free gel, with soothing seaweed extract, for people with very oily skin that suffer from acne or rosacea.

All our products are safe for children and moms-to-be. The cream relieves baby's diaper rash & eczema and softens and moisturizes rough areas on knees and cracked feet.                                 

BIOBALM ™ - A powerful antioxidant serum that inhibits free radical production and provides cellular and DNA protection from UV damage

Detoxifies the cells by removing cellular and DNA damaging materials that are responsible for adverse effects on the skin. Boosts the production of the water holding molecules present in the dermis and retains water. Induces the proliferation of antimicrobial peptides that keep skin infections at bay. Moderates inflammation. Relieves dryness and redness. Unclogs pores while replenishing the lipid barrier of the skin to block the penetration of allergens. Stimulates the regeneration of damaged cells.

50 Gram Bottle: $54.95